![]() Sciatica pain often is worsened with flexion of the lumbar spine, twisting, bending, or coughing.At up to 2 cm in diameter, the sciatic nerve is easily the largest nerve in the body. The sciatic nerve is made up of the L4 through S2 nerve roots which coalesce at the pelvis to form the sciatic nerve.Sciatica is a clinical diagnosis based on the presence of radiating pain in one leg, with or without the associated neurological deficits of parasthesia and muscle weakness, which are the direct result of sciatic nerve or sciatic nerve root pathology.A common mistake is referring to any low back pain or radicular leg pain as sciatica.Sciatica is a debilitating condition in which the patient experiences pain and/or paresthesias and/or weakness in the distribution of the sciatic nerve or an associated lumbosacral nerve root.
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